Grant Recipient Institutions since 2019

2023 Grant Awards

Albert Einstein College of Medicine

Principal Investigator: Teresa P. DiLorenzo, PhD
Project Title: Immunotherapeutic Strategies for the Induction and Maintenance of Remission in Type 1 Diabetes

Joslin Diabetes Center

Principal Investigator: Kyoungmin Park, PhD
Project Title: Effect of Anti-NFKBIB Autoantibody on Atherosclerosis in T1D Patients and Cardiovascular Disease Mouse Models

Joslin Diabetes Center

Principal Investigator: Tara Kaushal Maxwell, MD, PhD
Project Title: Harnessing Social Media to Increase Device Uptake and Improve Outcomes in Young People with Type 1 Diabetes

Boston College

Principal Investigator: Emrah Altindis, PhD
Project Title: Determine the Role of Microbiota-Derived Insulin Epitope Mimics in Type 1 Diabetes Onset

University of Alabama at Birmingham

Principal Investigator: Sasanka Ramanadham, PhD
Project Title: β-Cell- and Macrophage-Derived Lipids and Their Roles in Intercellular Signaling During T1D Development Regeneration

2022 Grant Awards

UCLA Medical Center-Lundquist Institute

Principal Investigator: Eiji Yoshihara, PhD
Project Title: Proliferative Functional Human Islet-Like Organoids

Joslin Diabetes Center

Principal Investigator: Thomas Serwold, PhD
Project Title: Establishing Immune Tolerance to Engrafted Beta Cells With 5-Module CARs

Washington University

Principal Investigator: Jeffrey R. Millman, PhD
Project Title: Deciphering Differentiation to Insulin-Secreting Islets for Diabetes Cellular Therapy

University of Colorado-Denver

Principal Investigator: Rachel S. Friedman, PhD
Project Title: Harnessing Myeloid Cell Mechanisms of Islet Protection

Joslin Diabetes Center

Principal Investigator: Jean Schaffer, MD
Project Title: β-Cell Ribosome Adaptations for Insulin Productions

2021 Grant Awards

Columbia University

Principal Investigator: Remi J. Creusot, PhD
Project Title: : A Novel mRNA Vaccine
for Type 1 Diabetes

Joslin Diabetes Center

Principal Investigator: Sarah Lessard, MSc, PhD
Project Title: : Identifying Therapeutic Targets to Improve Aerobic Capacity in People With T1D

University of California, San Francisco

Principal Investigator: Qizhi Tang, PhD
Project Title: Fortify Tregs to Restore Immune Tolerance in Autoimmune Diabetes

Columbia University

Principal Investigator: Xiojuan Chen, MD, PhD
Project Title: Regulating Human α- and δ- Cell Function in Pseudo-T1D Islets

Joslin Diabetes Center

Principal Investigator: Stephan Kissler, PhD
Project Title: Designing a Novel Drug to Protect Beta Cells Against Autoimmunity

University of Texas at Austin

Principal Investigator: John (Jack) Virostko, PhD, MSCI
Project Title: Machine Learning of MRI of the Pancreas in T1D and Application to Hispanic Population

Joslin Diabetes Center

Principal Investigator: Elena Toschi, PhD
Project Title: Evaluating the Use of Telehealth and Diabetes-Related Technologies in Older Adults With Type 1 Diabetes

University of California, San Francisco

Principal Investigator: Gregory M. KU, MD, PhD
Project Title: Whole Genome CRISPR Screens in Primary Human Pancreatic Beta Cells to Identify New Regulators of Survival and Proliferation

2020 Grant Awards

Joslin Diabetes Center

Principal Investigator: Cristina Aguayo-Mazzucato, MD, PhD
Project Title: Molecular Progression of Senescence and Generation of a SASP Signature in B-Cells

University of Kansas Medical Center Research Institute

Principal Investigator: Mary A. Markiewicz, PhD
Project Title: The Mechanism of Autoimmune Diabetes Protection Mediated by NKG2D-Induced GD8+Tcm

Joslin Diabetes Center

Principal Investigator: Mary Elizabeth Patti, MD
Project Title: The impact of Type 1 DM and Glycemic Control on Epigenetic Marks on Male Germ Cells

City of Hope National Medical Center

Principal Investigator: Defu Zeng, MD
Project Title: B Cell Regeneration in Established/Long-Standing Autoimmune Diabetic NOD Mice

University of California San Francisco

Principal Investigator: Matthias Hebrok, PhD
Project Title: The Role of BOLA3 in Beta Cell Function

University of California San Francisco

Principal Investigator: Julie B. Sneddon, PhD
Project Title: Engineering a Cellular Niche for Transplantation of Human Stem Cell-Derived Beta Cells

2019 Grant Awards

Joslin Diabetes Center

Principal Investigator: Peng Yi, PhD
Project Title: A whole genome CRISPR screen looking for factors that regulate beta cell neogenesis from pancreatic duct cells.

University of California San Francisco

Principal Investigator: Audrey V. Parent, PhD
Project Title: Immunoengineering of stem cell-derived insulin-producing cells for cell therapy and disease modeling.

University of Colorado Barbara Davis Center for Childhood Diabetes

Principal Investigator: Howard W. Davidson, PhD
Project Title: Immune changes in the honeymoon period at the single cell level.

Vanderbilt University Medical Center

Principal Investigator: Daniel Moore, MD, PhD
Project Title: How B Lymphocytes Prevent Transplantation Tolerance in T1D.

Joslin Diabetes Center

Principal Investigator: Rohit Kulkarni, MD, PhD
Project Title: Evaluating the therapeutic significance of SerpenB1 in T1D – a proof-of-concept proposal.

University of Michigan

Principal Investigator: Patrice Fort, PhD
Project Title: Inflammation in the diabetic human retina – role in disease progression.

Joslin Diabetes Center *

Principal Investigator: Aleksander Kostic, PhD
Project Title: Identifying T Cell Dynamics predictive of Type 1 Diabetes Immunopathogenesis.

Joslin Diabetes Center *

Principal Investigator: Monika Niewczas, MD, PhD, MPH.
Project Title: Complement Proteome and High Risk of Kidney Failure in Type 1 Diabetes

Brigham Young University *

Principal Investigator: Jeffery S. Tessem, PhD
Project Title: Defining beta cell heterogeneity to expand functional beta cell mass as a treatment for Type 1 Diabetes
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(*) Funding provided by the Thomas J. Beatson, Jr. Foundation Trust, a second charitable foundation established by Thomas J. Beatson, Jr. during his lifetime.